The alpha-fetoprotein enhancer region activates the albumin and alpha-fetoprotein promoters during liver development
نویسندگان
چکیده
منابع مشابه
MONOCLONAL ANTIBODIES TO HUMAN ALPHA-FETOPROTEIN
Alpha-fetoprotein (AFP), a serum glycoprotein belonging to the onco-developmental proteins group, serves as a marker both in cancer research and in studies concerning fetal development and fetal pathophysiology. Monoclonal anti-AFP antibodies are essential reagents in developing appropriate techniques for measurement of this protein. In this study, in order to produce anti-AFP monoclonal a...
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alpha-fetoprotein (AFP) gene expression occurs in the yolk sac, in the fetal liver and gut, and in the adult liver during regeneration and tumorigenesis. Two unlinked genes determine the level of AFP gene expression in adult mice: Afr1 regulates the basal level of expression in the normal adult liver, and Afr2 regulates the increase in expression during liver regeneration. It has been shown tha...
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Cytology in General Practice H. C. McLaren, F.R.C.O.G..... 350 Chronic Prostatitis Surgeon Commander N. J. Blacklock, F.R.C.S., and D. S. Reeves, M.R.C.PATH. 351 Trapped Nerves W. V. Applegate, M.D............................351 Distress of Dying R. C. Lamerton, M.R.C.S......................351 Alpha-fetoprotein and Gastric Carcinoma C. M. Castleden, M.R.C.P., and J. D. Davies, M.D . .............
متن کاملMaternal Serum Alpha-Fetoprotein Screening
Background: The maternal serum alpha-fetoprotein test (MSAFP) was developed to screen for neural tube defects. Little is known about the adoption of the MSAFP test. This study examines the effect of provider specialty and geographic location and patient insurance status on MSAFP test use in Washington State. Methods: We conducted a retrospective cohort study of MSAFP use in low-risk obstetric p...
متن کاملMicroheterogeneity of rat alpha-fetoprotein.
A purified and homogeneous preparation of rat AFP, as judged by both electrophoresis on Cellogel and immunoelectrophoresis, was separated into two components, AFPa and AFPb, by disc electrophoresis on 7% polyacrylamide gel. These two components had a definite difference in electrostatic net charge and gave only a single band on SDS-electrophoresis. Immunological reactivity or electrophoretic se...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2009
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2009.09.026